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VACCINATIONS and PREVENTATIVE MEDICINE
https://www.akc.org/expert-advice/health/puppy-shots-complete-guide/

Bordetella Bronchiseptica
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is highly infectious bacterium causes severe fits of coughing, whooping, vomiting, and, in rare cases, seizures and death. It is the primary cause of kennel cough.

Canine Distemper
A severe and contagious disease caused by a virus that attacks the respiratory, gastrointestinal (GI), and nervous systems of dogs, raccoons, skunks, and other animals, distemper spreads through airborne exposure (through sneezing or coughing) from an infected animal. The virus can also be transmitted by shared food and water bowls and equipment. It causes discharges from the eyes and nose, fever, coughing, vomiting, diarrhea, seizures, twitching, paralysis, and, often, death.

Canine Hepatitis
Infectious canine hepatitis is a highly contagious viral infection that affects the liver, kidneys, spleen, lungs, and the eyes of the affected dog. This disease of the liver is caused by a virus that is unrelated to the human form of hepatitis. Symptoms range from a slight fever and congestion of the mucous membranes to vomiting, jaundice, stomach enlargement, and pain around the liver.

Canine Parainfluenza
One of several viruses that can contribute to kennel cough.

Heartworm
These worms lodge in the right side of the heart and the pulmonary arteries (that send blood to the lungs), though they can travel through the rest of the body and sometimes invade the liver and kidneys. The worms can grow to 14 inches long and, if clumped together, block and injure organs. A new heartworm infection often causes no symptoms, though dogs in later stages of the disease may cough, become lethargic, lose their appetite or have difficulty breathing.

Leptospirosis
Unlike most diseases on this list, Leptospirosis is caused by bacteria, and some dogs may show no symptoms at all. Leptospirosis can be found worldwide in soil and water. It is a zoonotic disease, meaning that it can be spread from animals to people. When symptoms do appear, they can include fever, vomiting, abdominal pain, diarrhea, loss of appetite, severe weakness and lethargy, stiffness, jaundice, muscle pain, infertility, kidney failure (with or without liver failure).

Lyme Disease
Unlike the famous “bull’s-eye” rash that people exposed to Lyme disease often spot, no such telltale symptom occurs in dogs. Lyme disease (or borreliosis) is an infectious, tick-borne disease caused by a type of bacteria called a spirochete. Transmitted via ticks, an infected dog often starts limping, his lymph nodes swell, his temperature rises, and he stops eating. The disease can affect his heart, kidney, and joints, among other things, or lead to neurological disorders if left untreated.

Parvovirus
Parvo is a highly contagious virus that affects all dogs, but unvaccinated dogs and puppies less than four months of age are at the most risk to contract it. The virus attacks the gastrointestinal system and creates a loss of appetite, vomiting, fever, and often severe, bloody diarrhea. Extreme dehydration can come on rapidly and kill a dog within 48-to-72 hours, so prompt veterinary attention is crucial.

Rabies
Rabies is a viral disease of mammals that invades the central nervous system, causing headache, anxiety, hallucinations, excessive drooling, fear of water, paralysis, and death. It is most often transmitted through the bite of a rabid animal. Treatment within hours of infection is essential, otherwise, death is highly likely.

Puppy’s Age                                             Recommended Vaccinations                                                                                      Optional Vaccinations

6 — 8 weeks                                                            Distemper, parvovirus                                                                                             Bordetella

10 — 12 weeks                                                  DHPP (vaccines for distemper,
                                                                             adenovirus [hepatitis], parainfluenza, and parvovirus)                                       Influenza, Leptospirosis, Bordetella, Lyme                                                                                                                                                                                                                               disease per lifestyle as recommended by veterinarian

16 — 18 weeks                                                   DHPP, rabies,  Influenza, Lyme disease, Leptospirosis,  

                                                                                  Bordetella per lifestyle

12 — 16 months                                                DHPP, rabies                                                                                                                         Coronavirus, Leptospirosis, Bordetella, Lyme disease

Every 1 — 2 years                                             DHPP                                                                                                                                         Influenza, Coronavirus, Leptospirosis,    Bordetella, Lyme disease per lifestyle

Every 1 — 3 years                                           Rabies (as required by law)                                                                                                 none